
Overview
Areas of Expertise / Conditions Treated
- HIV (Human Immunodeficiency Virus Infection)
- HIV/AIDS
Academic Appointments
- Harold C. Neu Professor of Infectious Diseases (in Medicine) at the Columbia University Medical Center
Administrative Titles
- Associate Fellowship Program Director
- Chief, Division of Infectious Diseases
Hospital Affiliations
- NewYork-Presbyterian / Columbia University Irving Medical Center
- NewYork-Presbyterian Allen Hospital
Gender
- Female
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Phone Appointments
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Location(s)
Insurance Accepted
Aetna
- Aetna Signature Administrators
- AETNA Westchester MG Local 1199
- EPO
- HMO
- Medicare Managed Care
- NY Signature
- POS
- PPO
- Student Health
Affinity Health Plan
- Essential Plan
- Medicaid Managed Care
Amida Care
- Amida Care Westchester MG HIV SNP
- Amida Care Westchester MG Medicaid Managed Care
- Special Needs
Anthem Blue Cross Blue Shield
- Anthem Blue Cross Blue Shield ACN West
- Anthem Blue Cross Blue Shield Westchester MG Anthem
- Anthem Blue Cross Blue Shield Westchester MG Blue Access (Marketplace)
- Anthem Blue Cross Blue Shield Westchester MG Blue Card
- Anthem Blue Cross Blue Shield Westchester MG Connection
- Anthem Blue Cross Blue Shield Westchester MG Direct HMO
- Anthem Blue Cross Blue Shield Westchester MG Direct Share POS
- Anthem Blue Cross Blue Shield Westchester MG EPO
- Anthem Blue Cross Blue Shield Westchester MG FEP
- Anthem Blue Cross Blue Shield Westchester MG HMO
- Anthem Blue Cross Blue Shield Westchester MG Indemnity
- Anthem Blue Cross Blue Shield Westchester MG POS
- Anthem Blue Cross Blue Shield Westchester MG PPO
- Anthem Blue Cross Blue Shield Westchester MG Unicare
Cigna
- CIGNA Westchester MG FEP
- CIGNA Westchester MG HealthPartners
- CIGNA Westchester MG HMO
- CIGNA Westchester MG LocalPlus
- CIGNA Westchester MG Medical Indemnity
- CIGNA Westchester MG MVP
- CIGNA Westchester MG Open Access Plus (OAP)
- CIGNA Westchester MG POS
- CIGNA Westchester MG PPO
- CIGNA Westchester MG Priority Health
- CIGNA Westchester MG TPA
- EPO
- Great West (National)
- HMO
- POS
- PPO
Elderplan
- ElderPlan Westchester MG Medicare Managed Care
ElderServe
- Special Needs
Emblem/GHI
- Medicare Managed Care
- PPO
Emblem/HIP
- ConnectiCare
- EPO
- Essential Plan
- HMO
- Medicaid Managed Care
- Medicare Managed Care
- POS
- PPO
- Select Care (Exchange)
- Vytra
EmblemHealth
- EmblemHealth ACN West
- EmblemHealth Westchester MG Access I/II
- EmblemHealth Westchester MG Bridge Program
- EmblemHealth Westchester MG Bridge Program
- EmblemHealth Westchester MG Brooklyn Healthworks
- EmblemHealth Westchester MG Child Family Health Plus
- EmblemHealth Westchester MG DC37 Med-Team
- EmblemHealth Westchester MG Emblem Health
- EmblemHealth Westchester MG EPO
- EmblemHealth Westchester MG EPO
- EmblemHealth Westchester MG Federal Employee Benefit (FEHB)
- EmblemHealth Westchester MG Healthcare Partners (HCP)
- EmblemHealth Westchester MG HMO
- EmblemHealth Westchester MG Indemnity
- EmblemHealth Westchester MG Medicaid Managed Care
- EmblemHealth Westchester MG Medicare Managed Care
- EmblemHealth Westchester MG Millennium (Essential Plan 1-4
- 200-250)
- EmblemHealth Westchester MG NYCE PPO
- EmblemHealth Westchester MG POS
- EmblemHealth Westchester MG POS
- EmblemHealth Westchester MG PPO
- EmblemHealth Westchester MG PPO
- EmblemHealth Westchester MG Prime Network
- EmblemHealth Westchester MG Select Care (Exchange)
- EmblemHealth Westchester MG Select Care Network
- EmblemHealth Westchester MG Somos
- EmblemHealth Westchester MG Vytra
Empire Blue Cross/Blue Shield
- EPO
- HMO
- Medicare Managed Care
- PPO
Empire Blue Cross Blue Shield HealthPlus
- Child/Family Health Plus
- Essential Plan
- Individual Network (Exchange)
- Medicaid Managed Care
Fidelis Care
- Child/Family Health Plus
- Essential Plan
- Fidelis Care ACN West Child Family Health Plus
- Fidelis Care ACN West Dual Exchange
- Fidelis Care ACN West Essential Plan 1 and 2
- Fidelis Care ACN West Essential Plan 3 and 4
- Fidelis Care ACN West Exchange
- Fidelis Care ACN West Medicaid Managed Care and HARP
- Fidelis Care ACN West Medicare Managed Care
- Fidelis Care Westchester MG Ambetter (Exchange)
- Fidelis Care Westchester MG Essential Plan
- Fidelis Care Westchester MG Medicaid Managed Care
- Fidelis Care Westchester MG Medicare Dual Advantage
- Medicaid Managed Care
- Medicare Managed Care
Healthfirst
- Child/Family Health Plus
- Healthfirst ACN West Child Family Health Plus
- Healthfirst ACN West Essential Plan 1 and 2
- Healthfirst ACN West Essential Plan 3 and 4
- Healthfirst ACN West Exchange
- Healthfirst ACN West Medicaid Managed Care and HARP
- Healthfirst ACN West Medicare Managed Care
- Healthfirst Westchester MG Child Family Health Plus
- Healthfirst Westchester MG Essential Plan
- Healthfirst Westchester MG Exchange (Leaf Metal Plans)
- Healthfirst Westchester MG Medicaid Managed Care and HARP
- Healthfirst Westchester MG Medicare Managed Care
- Healthfirst Westchester MG NY Life Improvement Plan (SNP-DUAL Only)
- Healthfirst Westchester MG Qualified Health Plan
- Leaf (Exchange)
- Medicaid Managed Care
- Medicare Managed Care
Healthplus
- Healthplus Westchester MG Child Family Health Plus
- Healthplus Westchester MG Essential Plan
- Healthplus Westchester MG Exchange (Gatekeeper)
- Healthplus Westchester MG Managed Long Term Care (MLTC)
- Healthplus Westchester MG Medicaid Managed Care (Healthplus
- Amerigroup
- Wellpoint)
Healthspring
- Healthspring Westchester MG Medicare Managed Care
Healthspring (Cigna Medicare)
- Medicare Managed Care
Local 1199
- Local 1199
MagnaCare (National)
- MagnaCare
- Magnacare (National) Westchester MG ASC
- Magnacare (National) Westchester MG PPO
Medicaid
- Medicaid Westchester MG Traditional
Medicare
- Medicare Westchester MG Railroad
- Medicare Westchester MG Traditional
- Traditional Medicare
Molina Healthcare
- Molina Healthcare ACN West
- Molina Healthcare Westchester MG Medicare Managed Care (Senior Whole Health)
Multiplan
- Multiplan
- Multiplan Westchester MG EPO
- Multiplan Westchester MG HMO
- Multiplan Westchester MG PHCS
- Multiplan Westchester MG POS
- Multiplan Westchester MG PPO
MVP Health Care
- Child/Family Health Plus
- Essential Plan
- HMO
- Medicaid Managed Care
- MVP Health Care Westchester MG
UnitedHealthcare
- Empire Plan
- HMO
- Medicaid (Community Plan)
- Medicare Managed Care
- Oxford Freedom
- Oxford HMO
- Oxford Liberty
- POS
- PPO
- UnitedHealthcare ACN West
- UnitedHealthcare Westchester MG EPO
- UnitedHealthcare Westchester MG HMO
- UnitedHealthcare Westchester MG Oxford Freedom
- UnitedHealthcare Westchester MG Oxford HMO
- UnitedHealthcare Westchester MG Oxford Liberty
- UnitedHealthcare Westchester MG Oxford Metro
- UnitedHealthcare Westchester MG POS
- UnitedHealthcare Westchester MG PPO
VNS Health
- VNS Health ACN West Medicaid/Medicare Managed Care Advantage Plus
- VNS Health ACN West Select Health Medicaid Manage Care and HARP
- VNS Health Westchester MG Medicaid Managed Care
- VNS Health Westchester MG Medicare Managed Care
VNSNY CHOICE
- Medicare Managed Care
- SelectHealth
- Special Needs
WellCare
- Medicaid Managed Care
- Medicare Managed Care
- WellCare ACN West American Progressive Life & Health
- WellCare ACN West Managed Long Term Care (MLTC)
- WellCare ACN West Medicaid Managed Care and Child Family Health Plus (NJ)
- WellCare ACN West Medicaid Managed Long Term Services and Supports (MLTSS)
- WellCare ACN West Medicare Managed Care
- WellCare Westchester MG American Progressive Life
- WellCare Westchester MG New Jersey Services (Medicare Managed Care)
- WellCare Westchester MG NJ Managed Long Term Services and Supports (MLTSS)
- WellCare Westchester MG NJ Medicaid
- WellCare Westchester MG NY Medicare
World Trade Center Health Plan
- World Trade Center Health Plan
Credentials & Experience
Education & Training
- Columbia University College of Physicians and Surgeons
- Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center
- Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center
Board Certifications
- Infectious Disease
Research
Dr. Magdalena Sobieszczyk is the Harold Neu Professor of Infectious Diseases (in Medicine) and the Chief of Infectious Diseases at the Columbia University Irving Medical Center in New York. Dr. Sobieszczyk is a clinical virologist and the principal investigator of the NIH-funded Columbia Collaborative Clinical Trials Unit which has been advancing the science of HIV and emerging infections like SARS-CoV-2. Her research focuses on the development, testing, and implementation of biomedical interventions to prevent HIV and COVID-19 infections: specifically, vaccines, monoclonal antibodies, and pre-exposure prophylaxis (PrEP). She has led many large-scale NIH-funded international studies in these areas.
Since the start of the COVID-19 pandemic, she has established a prospective cohort to study epidemiology of COVID-19, cellular and antibody responses to primary infection and vaccination, and long-term effects of COVID-19 in diverse communities. She has led studies that focus on evaluating safety and efficacy of COVID-19 vaccines and other novel interventions to prevent and treat COVID-19. At the medical center, she oversaw the establishment of clinical management guidelines for treatment of COVID-19 and a multidisciplinary approach to the care of patients with long-COVID. She has been involved in educational and community outreach efforts to increase knowledge of COVID-19 vaccines and studies that address barriers to uptake. These efforts complement the ongoing clinical and translational research efforts that advance our understanding of this pathogen and are key elements of pandemic preparedness for other emerging or re-emerging pathogens.
Her HIV work also extends to testing interventions that address healthcare disparities and access to HIV care and prevention among women and minoritized MSM. This includes investigating gaps in the HIV prevention continuum and access to prevention services in the predominantly Latino and Black communities of northern Manhattan. The overarching aim of this body of research has been testing of interventions to support uptake, adherence, and persistence to PrEP and preparing for implementation of future biomedical interventions.
Research Interests
- HIV Clinical Trials
- HIV Vaccines
Selected Publications
- Sobieszczyk ME, Maaske J, Falsey AR, Sproule S, Robb ML, Frenck RW Jr, Tieu HV, Mayer KH, Corey L, Neuzil KM, Tong T, Brewinski Isaacs M, Janes H, Bansal H, Edwards LM, Green JA, Kelly EJ, Shoemaker K, Takas T, White T, Bhuyan P, Villafana T, Hirsch AI; AstraZeneca AZD1222 Clinical Study Group. Durability of protection and immunogenicity of AZD1222 (ChAdOx1 nCoV-19) COVID-19 vaccine over 6 months. J Clin Invest. 2022 Sep 15;132(18):e160565.
- Wang Q, Guo Y, Iketani S, Nair MS, Li Z, Mohri H, Wang M, Yu J, Bowen AD, Chang JY, Shah JG, Nguyen N, Chen Z, Meyers K, Yin MT, Sobieszczyk ME, Sheng Z, Huang Y, Liu L, Ho DD. Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5. Nature. 2022 Aug;608(7923):603-608.
- Falsey AR**, Sobieszczyk ME**, Hirsch I, Sproule S, Robb ML, Corey L, Neuzil KM, Hahn W, Hunt J, Mulligan MJ, McEvoy C, DeJesus E, Hassman M, Little SJ, Pahud BA, Durbin A, Pickrell P, Daar ES, Bush L, Solis J, Carr QO, Oyedele T, Buchbinder S, Cowden J, Vargas SL, Guerreros Benavides A, Call R, Keefer MC, Kirkpatrick BD, Pullman J, Tong T, Brewinski Isaacs M, Benkeser D, Janes HE, Nason MC, Green JA, Kelly EJ, Maaske J, Mueller N, Shoemaker K, Takas T, Marshall RP, Pangalos MN, Villafana T, Gonzalez-Lopez A; AstraZeneca AZD1222 Clinical Study Group. Phase 3 Safety and Efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 Vaccine. N Engl J Med. 2021 Dec 16;385(25):2348-2360. (** contributed equally)
- Wang P, Nair MS, Liu L, Iketani S, Luo Y, Guo Y, Wang M, Yu J, Zhang B, Kwong PD, Graham BS, Mascola JR, Chang JY, Yin MT, Sobieszczyk M, Kyratsous CA, Shapiro L, Sheng Z, Huang Y, Ho DD. Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7. Nature. 2021; 593, 130–135
- Zucker J, Gomez-Simmonds A, Purpura LJ, Shoucri S, LaSota E, Morley NE, Sovic BW, Castellon MA, Theodore DA, Bartram LL, Miko BA, Scherer ML, Meyers KA, Turner WC, Kelly M, Pavlicova M, Basaraba CN, Baldwin MR, Brodie D, Burkart KM, Bathon J, Uhlemann AC, Yin MT, Castor D, Sobieszczyk ME. Supervised Machine Learning Approach to Identify Early Predictors of Poor Outcome in Patients with COVID-19 Presenting to a Large Quaternary Care Hospital in New York City. J Clin Med. 2021 Aug
- Mehta M, Purpura LJ, McConville TH, Neidell MJ, Anderson MR, Bernstein EJ, Dietz DE, Laracy J, Gunaratne SH, Miller EH, Cheng J, Zucker J, Shah SS, Chaudhuri S, Gordillo CA, Patel SR, Guo TW, Karaaslan LE, Reshef R, Miko BA, Bathon JM, Pereira MR, Uhlemann AC, Yin MT, Sobieszczyk ME. What about tocilizumab? A retrospective study from a NYC Hospital during the COVID-19 outbreak. PLoS One. 2021 Apr 8;16(4):e0249349.
- Corey L, Gilbert PB, Juraska M, Montefiori DC, Morris L, Karuna ST, Edupuganti S, Mgodi NM, decamp AC, Rudnicki E, Huang Y, Gonzales P, Cabello. R, Orrell C, Lama JR, Laher. F, Lazarus EM, Sanchez. J, Frank. I, Hinojosa J, Sobieszczyk ME, Marshall KE, Mukwekwerere PG, Makhema J, Baden LR, Mullins JI, Williamson C, Hural J, McElrath JM, Bentley C, Takuva S, Gomez Lorenzo MM, Burns DN, Espy N, Randhawa AK, Kochar N, Piwowar-Manning E, Donnell DJ, Sista N, Andrew P, Kublin JG, Gray G, Ledgerwood JE, Mascola JR, Cohen MS. Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition. N Engl J Med 2021; 384:1003-1014
- Theodore DA, Greendyke WG, Miko B, Whittier S, Green DA, Shoucri S, Verna EC, Zucker J, Sobieszczyk ME, Aaron JG, Scully BE, Saiman L, Pereira M, Furuya EY. Cycle Thresholds Among Solid Organ Transplant Recipients Testing Positive for SARS-CoV-2. Transplantation. 2021 Jul 1;105(7):1445-1448
- Gulick RM, Sobieszczyk ME, Landry DW, Hollenberg AN. Prioritizing clinical research studies during the COVID-19 pandemic: lessons from New York City. J Clin Invest. 2020 Sep 1;130(9):4522-4524.
- Geleris J, Sun Y; Platt J, Zucker J, Baldwin M, Hripcsak G, Labella A, Manson DK, Kubin C, Barr RG, Sobieszczyk ME, Schluger NW. Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19. N Engl J Med 2020; 382:2411-2418
- Mgbako O, Miller EH, Santoro AF, Remien RH, Shalev N, Olender S, Gordon P, Sobieszczyk ME. COVID-19, Telemedicine, and Patient Empowerment in HIV Care and Research. AIDS Behav. 2020 Jul;24(7):1990-199
- Laracy J, Zucker J, Castor D, McMahon DJ, Guo TW, Yan M, Shalev N, Scherer M, Gordon P, Sobieszczyk M, Yin MT. HIV-1 Infection Does Not Change Disease Course or Inflammatory Pattern of SARS-CoV-2-Infected Patients Presenting at a Large Urban Medical Center in New York City. Open Forum Infect Dis. 2021 Jan 28;8(2):ofab029.
- Shalev N, Scherer M, LaSota ED, Antoniou P, Yin MT, Zucker J, Sobieszczyk ME. Clinical Characteristics and Outcomes in People Living With HIV Hospitalized for COVID-19. Clin Infect Dis. 2020 Nov 19;71(16):2294-2297
- Yumori C, Zucker J, Theodore D, Chang M, Carnevale C, Slowikowski J, LaSota E, Olender S, Gordon P, Cohall A, Sobieszczyk ME. Women Are Less Likely to Be Tested for HIV or Offered Preexposure Prophylaxis at the Time of Sexually Transmitted Infection Diagnosis. Sex Transm Dis. 2021 Jan;48(1):32-36.
- Zucker J, Carnevale C, Richards P, Slowikowski J, Borsa A, Gottlieb F, Vakkur I, Hyden C, Olender S, Cohall A, Gordon P, Sobieszczyk ME. Predictors of Disengagement in Care for Individuals Receiving Pre-Exposure Prophylaxis (PrEP). J Acquir Immune Defic Syndr. 2019 Apr 11
- Zucker J, Patterson B, Ellman T, Slowikowski J, Olender S, Gordon P, Morrison E, Sobieszczyk ME. Missed Opportunities for Engagement in the Prevention Continuum in a Predominantly Black and Latino Community in New York City. AIDS Patient Care and STDs. AIDS Patient Care and STDs. AIDS Patient Care STDS. 2018 Nov;32(11):432-437
- Zucker J, Carnevale C, Rai AJ, Gordon P, Sobieszczyk ME. Positive or Not, that is the Question: HIV Testing for Individuals on Pre-Exposure Prophylaxis (PrEP). J Acquir Immune Defic Syndr. 2018 Feb 21.
- Sobieszczyk ME, Werner L, Mlisana K, Naicker N, Feinstein A, Gray CM, Masson L, Passmore JS, Williamson C, Karim QA, Abdool Karim SS, Garret NJ. Metabolic syndrome after HIV acquisition in South African women. J Acquir Immune Defic Syndr. 2016 Jul 6. [Epub ahead of print]
- Williams WB, Liao HX, Moody MA, Kepler TB, Alam SM, Gao F, Wiehe K, Trama AM, Jones K, Zhang R, Song H, Marshall DJ, Whitesides JF, Sawatzki K, Hua A, Liu P, Tay MZ, Seaton KE, Shen X, Foulger A, Lloyd KE, Parks R, Pollara J, Ferrari G, Yu JS, Vandergrift N, Montefiori DC, Sobieszczyk ME, Hammer S, Karuna S, Gilbert P, Grove D, Grunenberg N, McElrath MJ, Mascola JR, Koup RA, Corey L, Nabel GJ, Morgan C, Churchyard G, Maenza J, Keefer M, Graham BS, Baden LR, Tomaras GD, Haynes BF.
20. HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies. Science. 2015 Aug 14;349(6249):aab1253.
- Dawson L, Garner S, Anude C, Ndebele P, Karuna S, Holt R, Broder G, Handibode J, Hammer S, Sobieszczyk ME. Testing the waters: ethical considerations for including PrEP in a phase IIb HIV vaccine efficacy trial. Clinical trials. Apr 7, 2015.
- Ellman TM, Hawkins K, Benitez J, Negron R, Chang S, Palmer S, Robertson V, Chiasson MA, Sobieszczyk ME. Representation of Latino and Black Men and Transgender women Screening and Enrolling into Preventive HIV Vaccine Trials in New York City. Vaccine. 2015;33(48):6809-15.
- Tang E., Sobieszczyk ME., Shu E., Gonzalez P., Sanchez J., Lama J. Provider Attitudes toward Oral Pre-Exposure Prophylaxis for HIV Prevention among High-Risk MSM in Lima, Peru. AIDS Research and Human Retroviruses 30(5):416-24.2014
- Ellman TM, Sexton ME, Warshafsky D, Sobieszczyk ME, Morrison E. A Forgotten Population: Older Adults Newly-Diagnosed with HIV. AIDS Patient Care and STDs. Volume 28, Number 10, 2014
- Hammer S.M., Sobieszczyk ME, Janes H. et al. Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine. New England J of Medicine, 2013 10.1056/NEJMoa1310566.
- Tieu HV, Rolland M, Hammer SM, Sobieszczyk ME. Translational Research Insights from Completed HIV Vaccine Efficacy Trials. Journal of AIDS 2013; (63) Supplement 2, July 1
- Janes H, Gilbert P, Buchbinder S, Kublin J, Sobieszczyk ME, and Hammer SM. In Pursuit of an HIV Vaccine: Designing Efficacy Trials in the Context of Partially Effective Nonvaccine Prevention Modalities. AIDS Research and Human Retroviruses 2013. ahead of print. doi:10.1089/aid.2012.0385
